ACOG Practice Bulletin: Prevention of Rh D Alloimmunization

Advances in the prevention and treatment of Rh D alloimmunization have been one of the great success stories of modern obstetrics. There is wide variation in prevalence rates of Rh D-negative individuals between regions, for example from 5% in India to 15% in North America. This document from the American College of Obstetricians and Gynecologists is to provide evidence-based guidance for the management of patients at risk of Rh D alloimmunization.